• gila@lemm.ee
    link
    fedilink
    English
    arrow-up
    13
    ·
    6 months ago

    Just as a thought experiment, what you’d really wanna do is change the salt nic formulation, i.e. the acidic compound which is added to freebase nicotine to convert it to a salt. This directly shapes the pharmacokinetics of the resulting nicotinic effect from vaping it, which is what leads to the common knowledge that salt nic hits harder, but doesn’t last as long as freebase. That isn’t universally true at all, but is a result of the salt formulations that are popular in the market.

    I worked with a scientist that once formulated a 20mg/mL solution for me that had similar throat hit to the 40mg/mL products I was using & had a very steep onset curve, and I found it to still be very satisfying even immediately after swapping. It wasn’t a successful product though because for the consumer, 20mg = 20mg & 40mg = 40mg

    Guess my point is that the novel ways of using tech to improve weaning off nicotine using vaping do legitimately exist, but they don’t have a place in a free market so we won’t have it while regulators stay luddites on the issue

    • Tekhne@sh.itjust.works
      link
      fedilink
      arrow-up
      5
      ·
      6 months ago

      That’s when you take a page out of the book of lightbulb manufacturers. On the box, CFLs and LEDs don’t show their actual wattage on the front, they write “100w equivalent” because that’s how people are used to measuring luminosity.

      • lad@programming.dev
        link
        fedilink
        English
        arrow-up
        2
        ·
        6 months ago

        I find it changing as of lately, as “W equivalent”, lumens, and actual Watts get printed on the bulbs’ package more often, sometimes even pulsation score or something. This really helps because actual Watts and lumens are quite independent now

        • Tekhne@sh.itjust.works
          link
          fedilink
          arrow-up
          2
          ·
          6 months ago

          Yeah exactly, but to get to that point we needed to message it to consumers as such for ~20 years. Similarly, in OPs example, the 20mg feels similarly to a 40mg, but with half the nicotine - clearly the measurement on the box is being used as a proxy for “how does this feel” (no clue if that has a measurement/is measureable) but could definitely message it similarly