Can confirm, I’m using a dock (from Razor) daily without problems. Hot switching doesn’t work though, you need to restart X/your display manager to connect or disconnect the eGPU. I’d recommend the gswitch utility to configure the graphics card to be used (on X11). Haven’t tested much on Wayland, but I know that at least Gnome (Wayland only) has trouble mixing eGPU and the internal display if that is important.
I use it for everything, because I connected my external monitors through the eGPU. https://wiki.archlinux.org/title/PRIME has a few methods for running only selected applications via the eGPU, but I haven’t tried them. Edit: See also https://wiki.archlinux.org/title/External_GPU#Xorg for eGPU specific setups.